Screening and functional validation of antibody drugs in vitro is a critical step during early antibody drug discovery, which determines the fate of the antibody drug candidates. GenScript has developed a series of cell-based in vitro bioassay to accommodate this particular need, ensuring smooth workflow and acquisition of the best lead. Cell lines can be custom-made for the purpose of immunization or serving as a binding and functional screening model for antibody drugs. IND-filing standard can be fulfilled upon request.
- 1 Growth inhibition assay;
- 2 GPCR-targeted agonist/antagonist assay;
- 3 Neutralization assay;
- 4 Immune checkpoint-targeted reporter gene assay;
- 5 Customized functional assay cell line construction;
- 6 Immune cell stimulation and multiplex cytokine release assay;
- 7 Mixed lymphocyte reaction;
- 8 Complement-dependent cytotoxicity assay;
- 9 Antibody-dependent cell cytotoxicity assay;
- 10 Antibody-dependent cellular phagocytosis assay;
- 11 Cellular characterization assay by flow cytometry;
- 12 Pseudovirus neutralization assay;
