The antibody sequence information is essential for monoclonal antibodies (mAbs) engineering, function optimization, database banking, and patent application. Our ISO9001 certified antibody sequencing service is your reliable choice to speed up and facilitate therapeutic antibody leads discovery and development. Tailored to meet your particular requirements, option with customized specifications is offered for antibody sequencing services at GenScript.
Our expertise helps you avoid common pitfalls when sequencing antibodies: 1) impurity of hybridoma cells, 2) mutations introduced by PCR, and 3) inaccurate or misaligned full sequences. Learn more from our success to overcome these problems »
|Hybridoma to sequence||Leader sequence & variable domain sequencing||$960*||10 business days||
|Full length antibody sequencing||$1,600*||10 business days|
|Sequence to recombinant antibody||1 mg recombinant Ab expression & one-step purification||$799@||18 business days||
|Antigen-rAb binding test by indirect ELISA||Free||5 business days||ELISA Binding report|
*Discount for batch order
#Upon your request
@Applicable to human IgG1, human IgG4 and mouse IgG2.
&QC data includes A280 for Antibody concentration, SDS-PAGE for purity assessment. Western Blot QC could be provided if requested with extra fee charged.
For sequencing services: Client will need to submit hybridoma cell samples (>1×106 cells) to GenScript.
For antigen-antibody binding confirmation service: Client will need to submit 20 μg antigen (>85% purity, >0.4 mg/ml) in the buffer without SDS, CHAPS, TWEEN, TRITON and PMSF.
For sequencing services: Final sequence report with leader sequences and CDR region annotated/ Final sequence report with leader sequences, constant region and CDR region annotated.
Sequence data, alignments of the heavy & light chains (free), sequencing plasmids containing sequenced antibody coding sequence (additional $100) expression construct containing full-length antibody coding sequence (additional $350) is available upon your option.
For antigen-antibody binding confirmation service: GenScript delivers 1 mg recombinant antibody synthesized from hybridoma sequence, QC, expression level and ELISA binding test report.
The client retains all rights to the sequence data and all related intellectual property.
GenScript offers our customers a one-stop solution for all outsourcing needs, providing comprehensive upstream and downstream services of monoclonal antibody sequencing service.
Avoid problems like gene loss & gene mutations, etc.
Accelerate Engineering work
Patent the sequences of your
unique variable domains
Cut in half the timeline for resupply of ab
Avoid introduction of animal-soured materials to generate immune response