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14 years' experience with over 400 Projects
Guarantee application in immunoassay development for PK and ADA analysis
Applied as critical reagent in IND filing and clinical trials
An anti-idiotype antibody (anti-ID Ab, see the schematic diagram) binds to the idiotype of another antibody, usually an antibody drug. An idiotype can be defined as the specific combination of idiotopes present within an antibodies complement determining regions. Since anti-ID Abs are capable of binding to antibody drugs within biological fluids, they are commonly used in preclinical setting for antibody drug pharmacokinetics (PK) and pharmacodynamics (PD). Due to the similarity between anti-ID Abs and anti-drug antibodies, anti-ID Abs are also commonly used as a reference standard for antibody drug immunogenicity, anti-drug antibody (ADA) studies and neutralization antibody measurement.
GenScript ProBio has 14 years experience in developing of highly sensitive and specific polyclonal and monoclonal anti-ID Abs to support your antibody drug development. We try to work as closely as possible with our customers to understand their specific downstream application in order to generate their perfect anti-ID. See our case studies »
Fit for capture ELISA & sandwich ELISA
8 weeks to delivery purified Anti-id pAb with guaranteed quantity
100% for blocking anti-id Ab
Positive control for ADA mensuration
QC standard: ELISA titer ≥ 1: 729,000; cross rate ≤ 2%;Stability: >5 years
#Other type: including but not limited to peptide, protein, ADC, SvFv & bispecific antibody.
PK and neutralization Ab analysis
21-27 (Regular)
13-14 (Express)
QC standard: ELISA titer ≥ 1: 729,000;Stability: >5 years
Guarantee to deliver one type of anti-id mAb (blocking or non-blocking)
QC standard: ELISA titer ≥1: 729,000;Stability: >5 years
Guarantee to deliver two types of anti-id mAb (blocking & non-blocking)Guarantee to deliver at least one anti-id mAb pair
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