GenScript ProBio is now licensing the CHOK1 cell line development system to biopharma companies for commercial use. Contact us for more information!
GenScript ProBio has 12 years of experience in mammalian cell line development, and is one of the earliest companies getting the CHO-K1 - CHO commercial license for commercial use and sublicense agreement from ECACC.
GenScript ProBio has two cell line development systems: wild-type cell line CHOK1-GenS and ADCC-enhanced cell line CHOK1-ADCC +. CHOK1-GenS cell line development system without chemical . Developed ADCC enhanced host cell line (CHOK1-ADCC+), which can produce afucosylated monoclonal antibodies with enhanced ADCC activity. They are in together with the high-expression proprietary pGenHT 1.0-UP vector, the yield titer can reach an mAb average: 5.4 g/L, protein up to: 13.6 g/L
180+ IND-Enabling Projects
26 IND Filings Supported
High antibody titer - average titer: mAb average: 5.4 g/L, protein up to: 13.6 g/L
Suitable for different type of molecules
Titer prior to cell culture up to 8.70 g/L
Excellent Stability in Scale-Up from 3L to 200L
CD16a 158V/F affinity (BLI)