G protein-coupled receptors (GPCRs) play important roles in cellular physiology and they are popular drug targets for various diseases. About 40% of approved drugs on the market belong to this category. Drug candidate screening and profiling is a critical step in GPCR-centered drug discovery. GenScript offers a comprehensive platform to speed up your GPCR drug discovery.
Key Features
- Over 150 different GPCR functional cell lines
- Customized GPCR stable cell line construction
- Multiple assay formats including calcium flux, cAMP determination, and Luciferase reporter gene assays
- Determine drug potency and efficacy in agonist, antagonist, inverse agonist and allosteric modulator modes
- Stringent QC standards with competitive prices
Figure 1. GenScript offers multiple functional assays to characterize your samples for agonist, inverse agonist, antagonist and allosteric modulator activities.
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