Bioanalytical development

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Bioanalytical Services

Bioanalytics is critical in drug discovery and development. GenScript ProBiopro vides a wide range of biophysical, biochemical and functional analysis for comprehensive ab/protein characterizations, using our state-of-art analytical platforms, including HTS iQue Screening system, BD FACS Calibur with HTS loader, Biacore 8k, LC-MS, and more.

With professional scientists and advanced facilities, GenScript ProBio provides individual analysis and integrated analytical solutions for clients from lead generation, lead optimization, drug candidates, stable cell line development, all the way up to pilot scale production.

>50

GenScript ProBio has developed over 50 bioanalytical methods.
>200

GenScript ProBio has supported over 200 NME programs.
>10,000

GenScript ProBio's largest HTS capacity is 10,000 molecule/day

Biochemical Assays

Affinity ranking/ measurement
Epitope mapping
Antibody sequencing

Key technologies/facilities:

Biacore 8k
Biacore T200
HTS iQue Screener
BD FACS Calibur with HTS loader

Cell-based Assays

Neutralization assay

Key technologies/facilities:

GenCripsr gene editing technology
Lentivirus gene knockout technology
FLIPRTetra
EnVison & PHERAStar
Top count
Liquid handler

Protein Analytics

Molecular weight analysis
Sequence coverage analysis
PTM analysis
Purity test
pI test

Charge variant analysis
N/C terminal sequence verification
N-glycan analysis
Impurity analysis (HCP,HCD…)

Key technologies/facilities:

Agilent HPLC1200,1260,UHPLC1290
Waters ACQUITY UPLC H-class Bio Core System
Sciex CE P/ACE MDQ Plus
SCIEX TripleTOF 4600 mass spectrometer
Applied Biosystems 7500 Real-Time PCR System